Schrödinger 2026-1 and broken jsc certs
Note: This post is pure google bait designed to help others who run into the same problem. We hope it helps! 16-April-2026: Correction – Schrödinger has documented this issue and a workaround at https://my.schrodinger.com/support/article/629509 You upgraded jobserverd, your functionality tests ran clean on the Slurm side, and a few hours later your scientists started complaining. […]
License-Aware Cloud HPC: Accelerating Discovery with Schrödinger, Cresset, and Posit
Summary Computational chemistry software licenses are among the most expensive line items in a drug discovery budget. When those licenses run on cloud HPC, poor integration creates problems: idle licenses burn money, contention between researchers stalls work, and GPU-heavy notebook sessions run around the clock even when no one is using them. It’s not just […]
PCS or ParallelCluster for Schrödinger Suite?
Everything you never wanted to know about PCS and PCluster for Schrödinger Workloads but have been forced to find out Why? It’s rare for me to simultaneously work on ParallelCluster and PCS for the same workload, and I learned some things, enough to justify writing some words about it. Hope someone finds it useful! Drivers […]
Research at Scale: Architecting HPC Infrastructure for a Leading Academic Medical Center
Summary A globally recognized academic medical center (AMC) for integrated healthcare and biomedical research faced a critical need to scale its data infrastructure to support accelerating demands in clinical operations and precision medicine. With well over 3,000 active clinical trials and more than 21,000 annual scientific publications, the scale of data production necessitated a platform […]
Modernizing Research HPC Authentication: Bridging Enterprise Identity and AWS ParallelCluster
Modern research institutions often hit a wall when modernizing access to high-performance computing environments. The compute infrastructure is already in place. Enterprise identity systems are already established. The challenge is enabling those systems to work together securely without creating friction for researchers or compromising institutional security requirements. BioTeam recently helped a major federal research institution […]
Bioinformatics at Scale: Building Computational Autonomy Across a Federal Research Institution
Overview As research teams increasingly rely on computational methods to analyze complex experimental data, many scientists face barriers to independently using bioinformatics tools and modern analytical workflows. A leading federal research institution sought to strengthen internal capability by improving researchers’ access to practical training, standardized workflows, and ongoing computational guidance. BioTeam partnered with the institution […]
Schrödinger at Scale: Enterprise HPC Infrastructure, Deployed in Minutes
Summary BioTeam partnered with a healthcare-focused investment firm whose mission is to advance healthcare innovation by funding innovative, new biotech organizations. These organizations required an automated, secure, scalable, and repeatable cloud-based HPC environment on AWS for their drug discovery pipelines. The client needed a compliant technology foundation that could be deployed at scale across multiple […]
Building a Centralized Scientific Data Ecosystem at a Large Research Institute
Overview Researchers at a leading NIH institute were generating increasingly complex scientific datasets, and the need for a modern, optimized data infrastructure became a key priority to support their cutting-edge research. Scientific data was distributed across various Network Attached Storage (NAS) systems, external hard drives, and instrument control computers without network access. There was […]
Bio-IT World’s Trends from the Trenches Podcast: Simplifying HPC Resources
Computing resources are no longer just pieces of tech—they’re scientific instruments. Moffitt Cancer Center’s Jarett DeAngelis, director of scientific information technology, and Shane Corder, senior HPC engineer, join cohost Jessica StLouis, senior scientific consultant at BioTeam , to discuss new approaches changing access to HPC resources and how platforms like Open OnDemand are simplifying the HPC experience for those unfamiliar with the system. They also share their thoughts on the future of HPC resources, what the Moffitt Cancer Center is planning, and what they expect to see in the field in the coming years.
Modernizing Hybrid Infrastructure for Clinical Diagnostics
Summary BioTeam partnered with a prominent clinical diagnostics organization to modernize its digital foundation. This engagement developed a high-level, cloud-smart, modernized strategy for the company’s existing digital backbone, specifically targeting digital image analysis and DNA sequencing to enhance efficiency and oversight and add new diagnostic capabilities. Key strategic recommendations of the project included: Modernize and […]