Local LLMs for real HPC work, Part II: writing complex real-world AWS IAM policies
Local LLMs for real HPC work — a series Part I: Two Macs, a test harness, and the speed numbers (published 15-Oct-2026) Part II: Writing complex real-world AWS IAM policies (this post) Part III: Root-causing failed Schrödinger jobs from the logs (future post) Part IV: Letting a local model audit and fix a repo on […]
Consulting Brief: ParallelCluster Guardrails When Prod Is Shared
Update 17-Oct-2026: the client’s SCP now lets our ParallelCluster operator role delete CloudWatch alarms and dashboards, so our clusters run with monitoring on again. See the update section. TL;DR It is counterintuitive, but it is safer to let AWS ParallelCluster deploy itself with broad permissions than to hand it pre-made roles. When ParallelCluster creates its […]
Claude Science and private AWS HPC compute
Claude Science knows how to connect via SSH to execute work on compute servers and HPC clusters That is good, but not very good. It’s 2026, and who wants to hang an SSH server out on the naked, public Internet? What I really need for Claude Science and my compute … This should be table-stakes […]
Your old AWS ParallelCluster stacks will NOT break in 2026
Note: This post is pure google bait designed to help others who run into the same problem. We hope it helps! We had been advising clients to rebuild older ParallelCluster stacks — the ones whose cleanup Lambdas are templated on python3.9 — by mid-2026, ahead of the published Lambda block dates. Those dates have moved. […]
Four FTRs and Counting…
BioTeam now has four offerings on the AWS Marketplace, each validated through the AWS Foundational Technical Review (FTR) process. BioTeam has been working with AWS since 2007, when the platform was still in beta. That history runs deep. Over nearly two decades, we have built, migrated, and optimized scientific computing environments for pharma, biotech, federal […]
License-Aware Cloud HPC: Accelerating Discovery with Schrödinger, Cresset, and Posit
Summary Computational chemistry software licenses are among the most expensive line items in a drug discovery budget. When those licenses run on cloud HPC, poor integration creates problems: idle licenses burn money, contention between researchers stalls work, and GPU-heavy notebook sessions run around the clock even when no one is using them. It’s not just […]
PCS or ParallelCluster for Schrödinger Suite?
Everything you never wanted to know about PCS and PCluster for Schrödinger Workloads but have been forced to find out Why? It’s rare for me to simultaneously work on ParallelCluster and PCS for the same workload, and I learned some things, enough to justify writing some words about it. Hope someone finds it useful! Drivers […]